ITM2B anticorps (C-Term)

N° du produit ABIN5531460

Détail du produit anti-ITM2B anticorps

Antigène: ITM2B (Integral Membrane Protein 2B (ITM2B))

Épitope: AA 218-247, C-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITM2B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ITM2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-247 amino acids from the C-terminal region of human ITM2B.

Isotype: Ig Fraction

Information d'application

Indications d'application: For IHC-P starting dilution is: 1:10~50

For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ITM2B

Antigène: ITM2B (Integral Membrane Protein 2B (ITM2B))

Autre désignation: ITM2B (ITM2B Produits)

Synonymes: anticorps ABRI, anticorps BRI, anticorps BRI2, anticorps BRICD2B, anticorps E25B, anticorps E3-16, anticorps FBD, anticorps imBRI2, anticorps AI256040, anticorps Bri, anticorps Bri2, anticorps Bricd2b, anticorps D14Sel6, anticorps E25BMM, anticorps itm2b, anticorps zgc:55770, anticorps zgc:85688, anticorps wu:fc05f02, anticorps MGC52745, anticorps MGC76131, anticorps ITM2B, anticorps itm2bl, anticorps wu:fb94b03, anticorps zgc:64142, anticorps integral membrane protein 2B, anticorps integral membrane protein 2Ba, anticorps integral membrane protein 2B L homeolog, anticorps integral membrane protein 2b, anticorps integral membrane protein 2Bb, anticorps ITM2B, anticorps Itm2b, anticorps itm2ba, anticorps itm2b.L, anticorps itm2b, anticorps itm2bb

Sujet: Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.

Poids moléculaire: 30 kDa

ID gène: 9445

UniProt: Q9Y287