PADI2 anticorps (C-Term)

N° du produit ABIN5531793

Détail du produit anti-PADI2 anticorps

Antigène: PADI2 (Peptidyl Arginine Deiminase, Type II (PADI2))

Épitope: AA 557-586, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PADI2 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PADI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-586 amino acids from the C-terminal region of human PADI2.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PADI2

Antigène: PADI2 (Peptidyl Arginine Deiminase, Type II (PADI2))

Autre désignation: PADI2 (PADI2 Produits)

Synonymes: anticorps PADI2, anticorps PAD-H19, anticorps PAD2, anticorps PDI2, anticorps Pdi, anticorps Pdi2, anticorps mKIAA0994, anticorps peptidyl arginine deiminase 2, anticorps peptidyl arginine deiminase, type II, anticorps protein-arginine deiminase type-2, anticorps peptidyl arginine deiminase, type II S homeolog, anticorps PADI2, anticorps padi2, anticorps LOC100357368, anticorps padi2.S, anticorps Padi2

Sujet: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq].

Poids moléculaire: 76 kDa

ID gène: 11240

UniProt: Q9Y2J8