This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This PLEKHF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human PLEKHF1.
PLEKHF1
Reactivité: Humain
WB, ELISA
Hôte: Lapin
Polyclonal
Biotin
Indications d'application
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
PLEKHF1
(Pleckstrin Homology Domain Containing, Family F (With FYVE Domain) Member 1 (PLEKHF1))
anticorps zgc:63897, anticorps PLEKHF1, anticorps APPD, anticorps LAPF, anticorps PHAFIN1, anticorps ZFYVE15, anticorps 1810013P09Rik, anticorps pleckstrin homology domain containing, family F (with FYVE domain) member 1, anticorps pleckstrin homology and FYVE domain containing 1, anticorps plekhf1, anticorps PLEKHF1, anticorps Plekhf1
Sujet
PLEKHF1 may induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.