RHOC anticorps (C-Term)

N° du produit ABIN5532681

Détail du produit anti-RHOC anticorps

Antigène: RHOC (Ras Homolog Gene Family, Member C (RHOC))

Épitope: AA 102-130, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHOC est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RHOC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the C-terminal region of human RHOC.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur RHOC

Antigène: RHOC (Ras Homolog Gene Family, Member C (RHOC))

Autre désignation: RHOC (RHOC Produits)

Synonymes: anticorps ARHC, anticorps LOC100221682, anticorps ARH9, anticorps H9, anticorps RHOH9, anticorps AI324259, anticorps Arh9, anticorps Arhc, anticorps CRHOC, anticorps ras homolog family member C L homeolog, anticorps ras homolog family member C, anticorps rhoc.L, anticorps RHOC, anticorps rhoc, anticorps Rhoc

Sujet: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Poids moléculaire: 22 kDa

ID gène: 389

UniProt: P08134

Pathways: Signalisation WNT, Cell-Cell Junction Organization