HYOU1 anticorps (AA 274-303)

N° du produit ABIN5532765

Détail du produit anti-HYOU1 anticorps

Antigène: HYOU1 (Hypoxia Up Regulated 1 (HYOU1))

Épitope: AA 274-303

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HYOU1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This HYOU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-303 amino acids from the Central region of human HYOU1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For IF starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur HYOU1

Antigène: HYOU1 (Hypoxia Up Regulated 1 (HYOU1))

Autre désignation: HYOU1 (HYOU1 Produits)

Synonymes: anticorps GRP-170, anticorps Grp170, anticorps HSP12A, anticorps ORP-150, anticorps ORP150, anticorps AI415631, anticorps CBP-140, anticorps Cab140, anticorps Orp150, anticorps id:ibd5056, anticorps wu:fd14c05, anticorps zgc:56019, anticorps HYOU1, anticorps orp150, anticorps GRP170, anticorps hypoxia up-regulated 1, anticorps hypoxia up-regulated protein 1, anticorps hypoxia up-regulated 1 S homeolog, anticorps HYOU1, anticorps Hyou1, anticorps hyou1, anticorps LOC100380749, anticorps hyou1.S

Sujet: HYOU1 belongs to the heat shock protein 70 family. The protein is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal.

Poids moléculaire: 111 kDa

ID gène: 10525

UniProt: Q9Y4L1

Pathways: ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome