This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This ABCD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-285 amino acids from the Central region of human ABCD1.
ABCD1
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Restrictions
For Research Use only
Format
Liquid
Concentration
0.32 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
ABCD1
(ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1))
anticorps ABC42, anticorps ALD, anticorps ALDP, anticorps AMN, anticorps RGD1562128, anticorps zgc:172102, anticorps ABCD1, anticorps Ald, anticorps Aldgh, anticorps ATP binding cassette subfamily D member 1, anticorps ATP-binding cassette, sub-family D (ALD), member 1, anticorps ATP-binding cassette sub-family D member 1, anticorps ATP binding cassette subfamily D member 1 L homeolog, anticorps ABCD1, anticorps Abcd1, anticorps abcd1, anticorps CpipJ_CPIJ013253, anticorps VDBG_05717, anticorps abcd1.L
Sujet
ABCD1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.