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Osteoprotegerin anticorps (AA 243-271)

TNFRSF11B Reactivité: Humain WB, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5533170
  • Antigène Voir toutes Osteoprotegerin (TNFRSF11B) Anticorps
    Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
    Épitope
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 243-271
    Reactivité
    • 61
    • 21
    • 18
    • 2
    • 2
    • 2
    • 2
    Humain
    Hôte
    • 50
    • 12
    • 2
    • 1
    Lapin
    Clonalité
    • 54
    • 11
    Polyclonal
    Conjugué
    • 43
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Osteoprotegerin est non-conjugé
    Application
    • 49
    • 29
    • 26
    • 18
    • 11
    • 8
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This TNFRSF11B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids from the Central region of human TNFRSF11B.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TNFRSF11B Anticorps primaire
  • Indications d'application
    For WB starting dilution is: 1:1000

    For IF starting dilution is: 1:10~50

    For IHC-P starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.42 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
    Autre désignation
    TNFRSF11B (TNFRSF11B Produits)
    Synonymes
    anticorps CD254, anticorps ODF, anticorps OPGL, anticorps OPTB2, anticorps RANKL, anticorps TRANCE, anticorps hRANKL2, anticorps sOdf, anticorps OCIF, anticorps OPG, anticorps TR1, anticorps Opg, anticorps ocif, anticorps opg, anticorps tr1, anticorps TNF superfamily member 11, anticorps TNF receptor superfamily member 11b, anticorps tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin), anticorps TNF receptor superfamily member 11B, anticorps tumor necrosis factor receptor superfamily member 11b S homeolog, anticorps tumor necrosis factor receptor superfamily, member 11b, anticorps TNFSF11, anticorps TNFRSF11B, anticorps Tnfrsf11b, anticorps tnfrsf11b.S
    Classe de substances
    Chemical
    Sujet
    The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
    Poids moléculaire
    46 kDa
    ID gène
    4982
    UniProt
    O00300
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