Seladin 1 anticorps (AA 218-246)

N° du produit ABIN5533376

Détail du produit anti-Seladin 1 anticorps

Antigène: Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))

Épitope: AA 218-246

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Seladin 1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This DHCR24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-246 amino acids from the Central region of human DHCR24.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Seladin 1

Antigène: Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))

Autre désignation: DHCR24 (DHCR24 Produits)

Synonymes: anticorps MGC82737, anticorps zgc:101638, anticorps DCE, anticorps Nbla03646, anticorps SELADIN1, anticorps seladin-1, anticorps 2310076D10Rik, anticorps 5830417J06Rik, anticorps mKIAA0018, anticorps 24-dehydrocholesterol reductase, anticorps 24-dehydrocholesterol reductase S homeolog, anticorps delta(24)-sterol reductase, anticorps DHCR24, anticorps dhcr24.S, anticorps dhcr24, anticorps LOC5575872, anticorps CpipJ_CPIJ000670, anticorps Dhcr24

Sujet: DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in DHCR24 gene have been associated with desmosterolosis. Also, reduced expression of DHCR24 gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.

Poids moléculaire: 60 kDa

ID gène: 1718

UniProt: Q15392