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ABCC5 anticorps (AA 625-652)

ABCC5 Reactivité: Humain WB, IHC (p), FACS Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5533648
  • Antigène Voir toutes ABCC5 Anticorps
    ABCC5 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))
    Épitope
    • 15
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 625-652
    Reactivité
    • 33
    • 20
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 42
    • 3
    • 3
    • 1
    Lapin
    Clonalité
    • 43
    • 6
    Polyclonal
    Conjugué
    • 19
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ABCC5 est non-conjugé
    Application
    • 34
    • 19
    • 13
    • 13
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This ABCC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 625-652 amino acids from the Central region of human ABCC5.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ABCC5 Anticorps primaire
  • Indications d'application
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100

    For FACS starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    ABCC5 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))
    Autre désignation
    ABCC5 (ABCC5 Produits)
    Synonymes
    anticorps ABC33, anticorps EST277145, anticorps MOAT-C, anticorps MOATC, anticorps MRP5, anticorps SMRP, anticorps pABC11, anticorps 2900011L11Rik, anticorps AI132311, anticorps Abcc5a, anticorps Abcc5b, anticorps Mrp5, anticorps abc33, anticorps abcc5, anticorps moat-c, anticorps moatc, anticorps mrp5, anticorps pabc11, anticorps smrp, anticorps ATP binding cassette subfamily C member 5, anticorps ATP-binding cassette, sub-family C (CFTR/MRP), member 5, anticorps ATP binding cassette subfamily C member 5 L homeolog, anticorps ABCC5, anticorps Abcc5, anticorps abcc5.L
    Sujet
    ABCC5 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs,6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients.
    Poids moléculaire
    161 kDa
    ID gène
    10057
    UniProt
    O15440
    Pathways
    Glycosaminoglycan Metabolic Process
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