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Aromatase anticorps (C-Term)

CYP19A1 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5533769
  • Antigène Voir toutes Aromatase (CYP19A1) Anticorps
    Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))
    Épitope
    • 16
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 453-485, C-Term
    Reactivité
    • 85
    • 57
    • 38
    • 30
    • 13
    • 13
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 69
    • 19
    • 1
    Lapin
    Clonalité
    • 73
    • 16
    Polyclonal
    Conjugué
    • 41
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Cet anticorp Aromatase est non-conjugé
    Application
    • 80
    • 21
    • 18
    • 15
    • 13
    • 13
    • 13
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    Immunogène
    This Aromatase (CYP19A1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 453-485 amino acids from the C-terminal region of human Aromatase (CYP19A1).
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CYP19A1 Anticorps primaire
  • Indications d'application
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))
    Autre désignation
    Aromatase (CYP19A1 Produits)
    Synonymes
    anticorps ARO, anticorps ARO1, anticorps CPV1, anticorps CYAR, anticorps CYP19, anticorps CYPXIX, anticorps P-450AROM, anticorps Aromatase, anticorps Cyp19, anticorps Cyp19a, anticorps p450arom, anticorps P450 arom, anticorps aro, anticorps cyp19, anticorps cyp19a, anticorps p450arom-A, anticorps P450AROM, anticorps Ar, anticorps ArKO, anticorps Int-5, anticorps Int5, anticorps CYP19P1, anticorps CYP19A1, anticorps CYP19a1, anticorps P450aromA, anticorps ar1, anticorps cypXIX, anticorps etID309862.18, anticorps zgc:136541, anticorps AroB, anticorps CYP19a2, anticorps P450aromB, anticorps cyp19b, anticorps zgc:92614, anticorps cyp19a1, anticorps cytochrome P450 family 19 subfamily A member 1, anticorps cytochrome P450, family 19, subfamily a, polypeptide 1, anticorps cytochrome P450 family 19 subfamily A member 1 L homeolog, anticorps aromatase, anticorps cytochrome P450 aromatase, anticorps cytochrome P450, family 19, subfamily A, polypeptide 1, anticorps cytochrome P450 19A1, anticorps cytochrome P450, family 17, subfamily A, polypeptide 1, anticorps cytochrome P450, family 19, anticorps cytochrome P450, family 19, subfamily A, polypeptide 1a, anticorps cytochrome P450, family 19, subfamily A, polypeptide 1b, anticorps cytochrome P450 19A1-like, anticorps CYP19A1, anticorps Cyp19a1, anticorps cyp19a1.L, anticorps SAV_2383, anticorps pfcyp19b-tstr, anticorps CYP19, anticorps cyp19a1a, anticorps cyp19a1b, anticorps LOC101174651
    Sujet
    CYP19A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in the gene encoding CYP19A1 can result in either increased or decreased aromatase activity, the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation.
    Poids moléculaire
    58 kDa
    ID gène
    1588
    UniProt
    P11511
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis
Support technique