MARK1 anticorps (C-Term)

N° du produit ABIN5534497

Détail du produit anti-MARK1 anticorps

Antigène: MARK1 (MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))

Épitope: AA 643-674, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MARK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MARK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 643-674 amino acids from the C-terminal region of human MARK.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur MARK1

Antigène: MARK1 (MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))

Autre désignation: MARK (MARK1 Produits)

Synonymes: anticorps MGC80341, anticorps MARK1, anticorps AW491150, anticorps B930025N23Rik, anticorps Emk3, anticorps Par-1c, anticorps mKIAA1477, anticorps mPar-1c, anticorps MARK, anticorps Par1c, anticorps MAP/microtubule affinity-regulating kinase 1 S homeolog, anticorps microtubule affinity regulating kinase 1, anticorps MAP/microtubule affinity-regulating kinase 1, anticorps MAP/microtubule affinity regulating kinase 1, anticorps mark1.S, anticorps MARK1, anticorps mark1, anticorps Mark1

Sujet: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

Poids moléculaire: 89 kDa

ID gène: 4139

UniProt: Q9P0L2

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2