PIK3 gamma anticorps (C-Term)

N° du produit ABIN5534583

Détail du produit anti-PIK3 gamma anticorps

Antigène: PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))

Épitope: AA 1041-1070, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIK3 gamma est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This PI3CKG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1041-1070 amino acids from the C-terminal region of human PI3CKG.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PIK3 gamma

Antigène: PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))

Autre désignation: PIK3CG (PIK3CG Produits)

Synonymes: anticorps PI3CG, anticorps PI3K, anticorps PI3Kgamma, anticorps PIK3, anticorps Pi3k, anticorps wu:fb15d07, anticorps zgc:77033, anticorps pi3k, anticorps 5830428L06Rik, anticorps p110gamma, anticorps p120-PI3K, anticorps phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma, anticorps phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma, anticorps si:rp71-17i16.5, anticorps PIK3CG, anticorps Pik3cg, anticorps pik3cg, anticorps si:rp71-17i16.5

Sujet: This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.

Poids moléculaire: 126 kDa

ID gène: 5294

UniProt: P48736

Pathways: Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Signalisation TLR, Inositol Metabolic Process, Hepatitis C, VEGF Signaling