PACRG anticorps (N-Term)

N° du produit ABIN5534593

Détail du produit anti-PACRG anticorps

Antigène: PACRG (PARK2 Co-Regulated (PACRG))

Épitope: AA 46-74, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PACRG est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PACRG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-74 amino acids from the N-terminal region of human PACRG.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PACRG

Antigène: PACRG (PARK2 Co-Regulated (PACRG))

Autre désignation: PACRG (PACRG Produits)

Synonymes: anticorps PACRG, anticorps GLUP, anticorps HAK005771, anticorps PARK2CRG, anticorps RP3-495O10.2, anticorps zgc:101786, anticorps RGD1561027, anticorps 1700008H23Rik, anticorps parkin coregulated, anticorps PARK2 co-regulated, anticorps PARK2 coregulated, anticorps PACRG, anticorps pacrg, anticorps Pacrg

Sujet: This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 33 kDa

ID gène: 135138

UniProt: Q96M98