TGIF1 anticorps (AA 208-237)

N° du produit ABIN5534743

Détail du produit anti-TGIF1 anticorps

Antigène: TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

Épitope: AA 208-237

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TGIF1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This TGIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human TGIF1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TGIF1

Antigène: TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

Autre désignation: TGIF1 (TGIF1 Produits)

Synonymes: anticorps HPE4, anticorps TGIF, anticorps AA959811, anticorps AI462167, anticorps Tgif, anticorps Tfig, anticorps fa06h05, anticorps fb33g11, anticorps zgc:55852, anticorps wu:fa06h05, anticorps wu:fb33g11, anticorps hpe4, anticorps tgif, anticorps tgif1, anticorps TGFB induced factor homeobox 1, anticorps TGFB-induced factor homeobox 1, anticorps TGFB induced factor homeobox 1 S homeolog, anticorps TGIF1, anticorps Tgif1, anticorps tgif1, anticorps tgif1.S

Sujet: The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described.

Poids moléculaire: 43 kDa

ID gène: 7050

UniProt: Q15583

Pathways: Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation