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UBE2D1 anticorps (C-Term)

UBE2D1 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5534798
  • Antigène Voir toutes UBE2D1 Anticorps
    UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
    Épitope
    • 15
    • 12
    • 9
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 111-140, C-Term
    Reactivité
    • 52
    • 21
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 49
    • 3
    Lapin
    Clonalité
    • 48
    • 4
    Polyclonal
    Conjugué
    • 17
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp UBE2D1 est non-conjugé
    Application
    • 41
    • 22
    • 16
    • 13
    • 13
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    Immunogène
    This UBE2D1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human UBE2D1.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product UBE2D1 Anticorps primaire
  • Indications d'application
    For IHC-P starting dilution is: 1:100

    For WB starting dilution is: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
    Autre désignation
    UBE2D1 (UBE2D1 Produits)
    Synonymes
    anticorps E2(17)KB1, anticorps SFT, anticorps UBC4/5, anticorps UBCH5, anticorps UBCH5A, anticorps ube2d1, anticorps wu:fc16h06, anticorps zgc:73096, anticorps e2(17)kb1, anticorps sft, anticorps ubc4/5, anticorps ubch5, anticorps ubch5a, anticorps ubiquitin conjugating enzyme E2 D1, anticorps ubiquitin-conjugating enzyme E2D 1, anticorps ubiquitin-conjugating enzyme E2D 1b, anticorps ubiquitin conjugating enzyme E2 D1 S homeolog, anticorps UBE2D1, anticorps Ube2d1, anticorps ube2d1b, anticorps ube2d1.S, anticorps ube2d1
    Sujet
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
    Poids moléculaire
    17 kDa
    ID gène
    7321
    UniProt
    P51668
    Pathways
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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