CDK14 anticorps (N-Term)

N° du produit ABIN5535105

Détail du produit anti-CDK14 anticorps

Antigène: CDK14 (Cyclin-Dependent Kinase 14 (CDK14))

Épitope: AA 45-72, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK14 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Mouse Cdk14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-72 amino acids from the N-terminal region of mouse Cdk14.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CDK14

Antigène: CDK14 (Cyclin-Dependent Kinase 14 (CDK14))

Autre désignation: Cdk14 (CDK14 Produits)

Synonymes: anticorps PFTK1, anticorps PFTAIRE1, anticorps Pftk1, anticorps mKIAA0834, anticorps pftaire1, anticorps pftk1, anticorps cyclin dependent kinase 14, anticorps cyclin-dependent kinase 14, anticorps cyclin-dependent kinase 14 L homeolog, anticorps CDK14, anticorps Cdk14, anticorps cdk14.L

Sujet: Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport (By similarity).

Poids moléculaire: 53 kDa

ID gène: 18647

UniProt: O35495