This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This POLR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 amino acids from the N-terminal region of human POLR1B.
POLR1B
Reactivité: Humain, Souris, Rat
WB, ELISA, IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
POLR1B
(Polymerase (RNA) I Polypeptide B, 128kDa (POLR1B))
anticorps RPOL-1l, anticorps MGC68946, anticorps 128kDa, anticorps D630020H17Rik, anticorps RPA116, anticorps RPA135, anticorps RPA2, anticorps Rpo1-2, anticorps RNA polymerase I subunit B, anticorps polymerase (RNA) I polypeptide B L homeolog, anticorps polymerase (RNA) I polypeptide B, 128kDa, anticorps polymerase (RNA) I polypeptide B, anticorps DNA-directed RNA polymerase I subunit RPA2, anticorps POLR1B, anticorps polr1b.L, anticorps polr1b, anticorps LOC100563266, anticorps LOC100634236, anticorps Polr1b
Sujet
Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).