TAF1 anticorps (C-Term)

N° du produit ABIN5535778

Détail du produit anti-TAF1 anticorps

Antigène: TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))

Épitope: AA 1863-1893, C-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAF1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1863-1893 amino acids from the C-terminal region of human TAF1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TAF1

Antigène: TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))

Autre désignation: TAF1 (TAF1 Produits)

Synonymes: anticorps BG:DS00004.13, anticorps CG17603, anticorps Dmel\\CG17603, anticorps EfW1, anticorps SR3-5, anticorps TAF, anticorps TAF1, anticorps TAF200, anticorps TAF230, anticorps TAF250, anticorps TAF250/230, anticorps TAFII-250, anticorps TAFII250, anticorps TAF[II]250, anticorps TAF[[II]], anticorps TAF[[II]]230, anticorps TAF[[II]]250, anticorps TAF[[II]]250/230, anticorps TFIID, anticorps TFIID TAF250, anticorps Taf1p, anticorps Taf200, anticorps Taf230, anticorps Taf250, anticorps Taf[[II]]250, anticorps cel, anticorps cell, anticorps d230, anticorps dTAF230, anticorps dTAF250, anticorps dTAFII250, anticorps dTAF[[II]]230, anticorps dTAF[[II]]250, anticorps dmTAF1, anticorps dmTAF[[II]]230, anticorps l(3)84Ab, anticorps p230, anticorps 250kDa, anticorps AU015687, anticorps B430306D02Rik, anticorps Ccg-1, anticorps Ccg1, anticorps KAT4, anticorps N-TAF1, anticorps Taf2a, anticorps RGD1562050, anticorps BA2R, anticorps CCG1, anticorps CCGS, anticorps DYT3, anticorps DYT3/TAF1, anticorps NSCL2, anticorps OF, anticorps P250, anticorps TAF2A, anticorps XDP, anticorps TAF(II)250, anticorps p250, anticorps TBP-associated factor 1, anticorps TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa, anticorps transcription initiation factor TFIID subunit 1, anticorps transcription initiation factor TFIID, subunit TAF1, anticorps TATA-box binding protein associated factor 1, anticorps Taf1, anticorps TAF1, anticorps LOC5567420, anticorps CpipJ_CPIJ003658, anticorps TAF11.1, anticorps HAF1501, anticorps HAF1502, anticorps LOC100457071

Sujet: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. This subunit contains two independent protein kinase domains at the N and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme. This gene is part of a complex transcriptional unit (TAF1/DYT3), wherein some products share exons with TAF1 as well as additional exons downstream.

Poids moléculaire: 213 kDa

ID gène: 6872

UniProt: P21675