NAE1 anticorps (C-Term)

N° du produit ABIN5535814

Détail du produit anti-NAE1 anticorps

Antigène: NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

Épitope: AA 430-459, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAE1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This NAE1 (APPBP1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 430-459 amino acids from the C-terminal region of human NAE1 (APPBP1).

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur NAE1

Antigène: NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

Autre désignation: NAE1 (NAE1 Produits)

Synonymes: anticorps APPBP1, anticorps CG7828, anticorps Dmel\\CG7828, anticorps anon-WO0140519.225, anticorps dAPP-BP1, anticorps dAPPBP1, anticorps A-116A10.1, anticorps ula-1, anticorps Appbp1, anticorps 59kDa, anticorps appbp1, anticorps zgc:66148, anticorps beta-Amyloid precursor protein binding protein 1, anticorps NEDD8 activating enzyme E1 subunit 1, anticorps NEDD8 activating enzyme E1 subunit 1 S homeolog, anticorps nedd8 activating enzyme E1 subunit 1, anticorps NEDD8-activating enzyme E1 regulatory subunit, anticorps APP-BP1, anticorps NAE1, anticorps Nae1, anticorps nae1.S, anticorps nae1, anticorps ula-1

Sujet: APPBP1 binds to the beta-amyloid precursor protein, a cell surface protein with signal-transducing properties thought to play a role in the pathogenesis of Alzheimer's disease. In addition, this protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. APPB1 is required for cell cycle progression through the S/M checkpoint.

Poids moléculaire: 60 kDa

ID gène: 8883

UniProt: Q13564