Connexin 31 anticorps (C-Term)

N° du produit ABIN5536021

Détail du produit anti-Connexin 31 anticorps

Antigène: Connexin 31 (GJB3) (Gap Junction Protein, beta 3, 31kDa (GJB3))

Épitope: AA 227-257, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Connexin 31 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This Connexin 31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-257 amino acids from the C-terminal region of human Connexin 31.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Connexin 31

Antigène: Connexin 31 (GJB3) (Gap Junction Protein, beta 3, 31kDa (GJB3))

Autre désignation: Connexin 31 (GJB3 Produits)

Synonymes: anticorps CX31, anticorps DFNA2, anticorps DFNA2B, anticorps EKV, anticorps Cnx31, anticorps Cx31, anticorps D4Wsu144e, anticorps Gjb-3, anticorps ekv, anticorps cx31, anticorps dfna2, anticorps gjb3b, anticorps dfna2b, anticorps connexin-31, anticorps gap junction protein beta 3, anticorps gap junction protein, beta 3, anticorps gap junction protein beta 3 L homeolog, anticorps GJB3, anticorps Gjb3, anticorps gjb3.L, anticorps gjb3

Sujet: Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Defects in GJB3 have been linked to erythrokeratodermia variabilis (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis. Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.

Poids moléculaire: 31 kDa

ID gène: 2707

UniProt: O75712

Pathways: Sensory Perception of Sound