MAPK15 anticorps (N-Term)

N° du produit ABIN5536093

Détail du produit anti-MAPK15 anticorps

Antigène: MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))

Épitope: AA 32-61, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK15 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This MAPK15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human MAPK15.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur MAPK15

Antigène: MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))

Autre désignation: MAPK15 (MAPK15 Produits)

Synonymes: anticorps MGC138052, anticorps MGC99048, anticorps erk7, anticorps zgc:110345, anticorps ERK7, anticorps ERK8, anticorps BC048082, anticorps Erk7, anticorps ATMPK15, anticorps F25P22.9, anticorps F25P22_9, anticorps MAP kinase 15, anticorps mitogen-activated protein kinase 15, anticorps mitogen-activated protein kinase 15 L homeolog, anticorps MAP kinase 15, anticorps MAPK15, anticorps mapk15.L, anticorps mapk15, anticorps Tsp_00300, anticorps Mapk15, anticorps MPK15

Sujet: The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.

Poids moléculaire: 60 kDa

ID gène: 225689

UniProt: Q8TD08