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PABPC4 anticorps (AA 219-247)

PABPC4 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5536583
  • Antigène Voir toutes PABPC4 Anticorps
    PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))
    Épitope
    • 7
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 219-247
    Reactivité
    • 37
    • 14
    • 14
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 36
    • 1
    Lapin
    Clonalité
    • 37
    Polyclonal
    Conjugué
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PABPC4 est non-conjugé
    Application
    • 30
    • 17
    • 11
    • 7
    • 5
    • 3
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This PABPC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-247 amino acids from the Central region of human PABPC4.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PABPC4 Anticorps primaire
  • Indications d'application
    For WB starting dilution is: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))
    Autre désignation
    PABPC4 (PABPC4 Produits)
    Synonymes
    anticorps cb12, anticorps sb:cb12, anticorps PABP, anticorps ePAB, anticorps ePABP, anticorps APP-1, anticorps APP1, anticorps PABP4, anticorps iPABP, anticorps polyadenylate-binding protein 4, anticorps poly(A) binding protein, cytoplasmic 4, anticorps poly(A) binding protein, cytoplasmic 4 (inducible form), anticorps poly(A) binding protein cytoplasmic 4 L homeolog, anticorps poly(A) binding protein cytoplasmic 4, anticorps Bm1_06880, anticorps Pabpc4, anticorps pabpc4, anticorps pabpc4.L, anticorps PABPC4
    Sujet
    Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Poids moléculaire
    71 kDa
    ID gène
    8761
    UniProt
    Q13310
    Pathways
    SARS-CoV-2 Protein Interactome
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