IL5RA anticorps (C-Term)

N° du produit ABIN5536641

Détail du produit anti-IL5RA anticorps

Antigène: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Épitope: AA 391-420, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL5RA est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This IL5RA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-420 amino acids from the C-terminal region of human IL5RA.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.36 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur IL5RA

Antigène: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Autre désignation: IL5RA (IL5RA Produits)

Synonymes: anticorps MGC86517, anticorps IL5RA, anticorps il5r, anticorps cdw125, anticorps hsil5r3, anticorps gpIL-5ra, anticorps CD125, anticorps CDw125, anticorps HSIL5R3, anticorps IL5R, anticorps Il5r, anticorps interleukin 5 receptor subunit alpha L homeolog, anticorps interleukin 5 receptor subunit alpha, anticorps interleukin 5 receptor, alpha, anticorps il5ra.L, anticorps IL5RA, anticorps il5ra, anticorps Il5ra

Sujet: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.

Poids moléculaire: 48 kDa

ID gène: 3568

UniProt: Q01344

Pathways: Signalistation JAK/STAT