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COCH anticorps (C-Term)

COCH Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5536739
  • Antigène Voir toutes COCH Anticorps
    COCH (Cochlin (COCH))
    Épitope
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 492-520, C-Term
    Reactivité
    • 48
    • 13
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 46
    • 2
    Lapin
    Clonalité
    • 48
    Polyclonal
    Conjugué
    • 21
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp COCH est non-conjugé
    Application
    • 37
    • 27
    • 16
    • 13
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This COCH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 492-520 amino acids from the C-terminal region of human COCH.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product COCH Anticorps primaire
  • Indications d'application
    For WB starting dilution is: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    COCH (Cochlin (COCH))
    Autre désignation
    COCH (COCH Produits)
    Synonymes
    anticorps AW122937, anticorps Coch-5B2, anticorps D12H14S564E, anticorps COCH-5B2, anticorps COCH5B2, anticorps DFNA9, anticorps cochlin, anticorps Coch, anticorps COCH
    Sujet
    The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94 % and 79 % amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. [provided by RefSeq].
    Poids moléculaire
    59 kDa
    ID gène
    1690
    UniProt
    O43405
    Pathways
    Sensory Perception of Sound
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