PKMYT1 anticorps (N-Term)

N° du produit ABIN5537158

Détail du produit anti-PKMYT1 anticorps

Antigène: PKMYT1 (Protein Kinase, Membrane Associated tyrosine/threonine 1 (PKMYT1))

Épitope: AA 114-143, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKMYT1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Mouse Pkmyt1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-143 amino acids from the N-terminal region of mouse Pkmyt1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PKMYT1

Antigène: PKMYT1 (Protein Kinase, Membrane Associated tyrosine/threonine 1 (PKMYT1))

Autre désignation: Pkmyt1 (PKMYT1 Produits)

Synonymes: anticorps MYT1, anticorps 6230424P17, anticorps AW209059, anticorps Myt1, anticorps RGD1305434, anticorps myt1, anticorps protein kinase, membrane associated tyrosine/threonine 1, anticorps protein kinase, membrane associated tyrosine/threonine 1 S homeolog, anticorps PKMYT1, anticorps pkmyt1, anticorps Pkmyt1, anticorps pkmyt1.S

Sujet: Pkmyt1 acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development (By similarity).

Poids moléculaire: 54 kDa

ID gène: 268930

UniProt: Q9ESG9

Pathways: Mitotic G1-G1/S Phases, M Phase