NSUN2 anticorps (AA 423-451)

N° du produit ABIN5537213

Détail du produit anti-NSUN2 anticorps

Antigène: NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

Épitope: AA 423-451

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NSUN2 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NSUN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 423-451 amino acids from the Central region of human NSUN2.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur NSUN2

Antigène: NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

Autre désignation: NSUN2 (NSUN2 Produits)

Synonymes: anticorps D13Wsu123e, anticorps Misu, anticorps MISU, anticorps MRT5, anticorps SAKI, anticorps TRM4, anticorps RGD1311954, anticorps NOL1/NOP2/Sun domain family member 2, anticorps NOP2/Sun RNA methyltransferase family member 2, anticorps NOP2/Sun RNA methyltransferase family, member 2, anticorps NOP2/Sun RNA methyltransferase family member 2 S homeolog, anticorps Nsun2, anticorps NSUN2, anticorps nsun2.S

Sujet: Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. NSUN2 encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA) (Brzezicha et al., 2006 [PubMed 17071714]).

Poids moléculaire: 86 kDa

ID gène: 54888

UniProt: Q08J23