PDE4B anticorps (AA 189-217)

N° du produit ABIN5537288

Détail du produit anti-PDE4B anticorps

Antigène: PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

Épitope: AA 189-217

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE4B est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PDE4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-217 amino acids from the Central region of human PDE4B.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.26 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PDE4B

Antigène: PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

Autre désignation: PDE4B (PDE4B Produits)

Synonymes: anticorps dpde4, anticorps pde4b5, anticorps pdeivb, anticorps Dpde4, anticorps R74983, anticorps dunce, anticorps PDE4/IVb, anticorps Pde4B1, anticorps Pde4B2, anticorps Pde4B3, anticorps Pde4B4, anticorps DPDE4, anticorps PDE4B5, anticorps PDEIVB, anticorps phosphodiesterase 4B, anticorps phosphodiesterase 4B, cAMP specific, anticorps phosphodiesterase 4B S homeolog, anticorps pde4b, anticorps PDE4B, anticorps Pde4b, anticorps pde4b.S

Sujet: This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Poids moléculaire: 83 kDa

ID gène: 5142

UniProt: Q07343

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction