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POLR3C anticorps (AA 202-230)

POLR3C Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5537338
  • Antigène Voir toutes POLR3C Anticorps
    POLR3C (Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C))
    Épitope
    • 15
    • 9
    • 8
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 202-230
    Reactivité
    • 48
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 44
    • 4
    Lapin
    Clonalité
    • 47
    • 1
    Polyclonal
    Conjugué
    • 20
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp POLR3C est non-conjugé
    Application
    • 43
    • 21
    • 13
    • 5
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This POLR3C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-230 amino acids from the Central region of human POLR3C.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product POLR3C Anticorps primaire
  • Indications d'application
    For WB starting dilution is: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.45 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    POLR3C (Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C))
    Autre désignation
    POLR3C (POLR3C Produits)
    Synonymes
    anticorps rpc3, anticorps rpc62, anticorps 4933407E01Rik, anticorps RPC3, anticorps RPC62, anticorps zgc:56348, anticorps polymerase (RNA) III (DNA directed) polypeptide C (62kD) S homeolog, anticorps RNA polymerase III subunit C, anticorps polymerase (RNA) III (DNA directed) polypeptide C (62kD), anticorps polymerase (RNA) III (DNA directed) polypeptide C, anticorps polr3c.S, anticorps POLR3C, anticorps polr3c, anticorps Polr3c
    Sujet
    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway.
    Poids moléculaire
    61 kDa
    ID gène
    10623
    UniProt
    Q9BUI4
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