RIPK3 anticorps (C-Term)

N° du produit ABIN5537455

Détail du produit anti-RIPK3 anticorps

Antigène: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Épitope: AA 480-509, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIPK3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RIPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 480-509 amino acids from the C-terminal region of human RIPK3.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:500

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur RIPK3

Antigène: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Autre désignation: RIPK3 (RIPK3 Produits)

Synonymes: anticorps RIPK3, anticorps RIP3, anticorps 2610528K09Rik, anticorps AW107945, anticorps Rip3, anticorps Hcyp2, anticorps receptor interacting serine/threonine kinase 3, anticorps receptor interacting serine/threonine kinase 3 S homeolog, anticorps receptor-interacting serine-threonine kinase 3, anticorps RIPK3, anticorps ripk3.S, anticorps Ripk3

Sujet: The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

Poids moléculaire: 57 kDa

ID gène: 11035

UniProt: Q9Y572

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades