RND3 anticorps (AA 133-165)

N° du produit ABIN5537459

Détail du produit anti-RND3 anticorps

Antigène: RND3 (rho Family GTPase 3 (RND3))

Épitope: AA 133-165

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RND3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This ARHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-165 amino acids from the Central region of human ARHE.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur RND3

Antigène: RND3 (rho Family GTPase 3 (RND3))

Autre désignation: ARHE (RND3 Produits)

Synonymes: anticorps ARHE, anticorps Rho8, anticorps RhoE, anticorps memB, anticorps MGC83857, anticorps 2610017M01Rik, anticorps AI661404, anticorps Arhe, anticorps Rhoe, anticorps RHOE, anticorps arhe, anticorps id:ibd2712, anticorps id:ibd2919, anticorps rho8, anticorps rnd3, anticorps wu:fc39h07, anticorps zgc:73080, anticorps wu:fd06e12, anticorps zgc:92324, anticorps Rho family GTPase 3, anticorps Rho family GTPase 3 L homeolog, anticorps Rho family GTPase 3a, anticorps Rho family GTPase 3b, anticorps RND3, anticorps rnd3.L, anticorps Rnd3, anticorps rnd3a, anticorps rnd3b

Sujet: Members of the Rho family of Ras-related GTPases, such as ARHE, regulate the organization of the actin cytoskeleton in response to extracellular growth factors. Like Ras (MIM 190020), Rho family members appear to cycle between an inactive GDP-bound form and an active GTP-bound form. Three major regulators of Rho activity have been identified: RhoGDIs, which interact with the GDP-bound Rho proteins to keep them in a resting complex (see MIM 601925), GEFs, which promote GDP/GTP exchange leading to activation of Rho proteins (see MIM 601855), and GAPs, which stimulate GTP hydrolysis and return the activated Rho protein to its inactive form (see MIM 602680) (Nobes et al., 1998 [PubMed 9531558]).

Poids moléculaire: 27 kDa

ID gène: 390

UniProt: P61587