This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This VPS11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 772-800 amino acids from the C-terminal region of human VPS11.
VPS11
Reactivité: Humain
WB, IP
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
VPS11
(Vacuolar Protein Sorting 11 Homolog (VPS11))
anticorps zgc:112329, anticorps ATVPS11, anticorps F5G3.7, anticorps F5G3_7, anticorps vacuolar protein sorting 11, anticorps DDBDRAFT_0204454, anticorps DDBDRAFT_0234135, anticorps DDB_0204454, anticorps DDB_0234135, anticorps end1, anticorps pep5, anticorps hvps11, anticorps rnf108, anticorps 1200011A11Rik, anticorps END1, anticorps PEP5, anticorps RNF108, anticorps hVPS11, anticorps VPS11, CORVET/HOPS core subunit, anticorps vacuolar protein sorting 11, anticorps vacuolar protein sorting protein 11, anticorps VPS11, CORVET/HOPS core subunit S homeolog, anticorps Vacuolar peripheral membrane protein similar to S. cerevisiae PEP5 (YMR231W); C terminus is almost identical to nonallelic CaP19.1278, anticorps 7-fold repeat in clathrin and VPS proteins repeat-containing protein, anticorps vacuolar protein sorting-associated protein 11 homolog, anticorps VPS11 CORVET/HOPS core subunit, anticorps VPS11, anticorps vps11, anticorps MCYG_02909, anticorps vps11.S, anticorps LOC100632536, anticorps Vps11
Sujet
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.