USP6 anticorps (C-Term)

N° du produit ABIN5537691

Détail du produit anti-USP6 anticorps

Antigène: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Épitope: AA 1280-1310, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP6 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This USP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1280-1310 amino acids from the C-terminal region of human USP6.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.44 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur USP6

Antigène: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Autre désignation: USP6 (USP6 Produits)

Synonymes: anticorps HRP1, anticorps TRE2, anticorps TRE17, anticorps Tre-2, anticorps USP6-short, anticorps ubiquitin specific peptidase 6, anticorps ubiquitin carboxyl-terminal hydrolase 6, anticorps Ubiquitin carboxyl-terminal hydrolase 6, putative, anticorps USP6, anticorps CNG04540, anticorps ANI_1_2152104, anticorps AOR_1_208094, anticorps MCYG_00569, anticorps CC1G_15273, anticorps MGYG_01395, anticorps CGB_G0160W, anticorps LOC100282385

Sujet: Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

Poids moléculaire: 159 kDa

ID gène: 9098

UniProt: P35125