This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This SERPINB11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-196 amino acids from the Central region of human SERPINB11.
SERPINB11
Reactivité: Humain
WB, IF (p)
Hôte: Lapin
Polyclonal
Alexa Fluor 680
Indications d'application
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
SERPINB11
(Serine (Or Cysteine) Peptidase Inhibitor, Clade B (Ovalbumin), Member 11 (SERPINB11))
anticorps 2310046M08Rik, anticorps AU015399, anticorps EPIPIN, anticorps SERPIN11, anticorps serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11, anticorps serpin family B member 11 (gene/pseudogene), anticorps Serpinb11, anticorps SERPINB11
Sujet
SerpinB11 is a serine proteinase inhibitor of the ovalbumin-like B clade of serpins. It was first discovered in human lung and prostate. Little is known about SerpinB11 tissue distribution and function. Splice variants of 305, 278 and 190 amino acids have been reported, with predicted masses of 33.97, 31.6 and 21.1 kDa respectively, and pIs of 8.11, 9.03 and 6.07 respectively. The 305 and 190 amino acid forms share the same aminoterminus as the 392 amino acid form. The 305 amino acid form has a deletion in residues 120-206, of the 392 amino acid form. The 190 amino acid form has a deletion in residues 57-259 relative to the long form. The 278 amino acid form starts at the third methionine, relative to the long form. All four forms contain the reactive center loop of the long form, but it is unknown if the shorter forms are active serpins. The predicted isoelectric points of SerpinB11 are significantly more basic than the other B clade serpins, and suggest a different localization or function for this serpin.