SGEF anticorps (AA 378-406)

N° du produit ABIN5538661

Détail du produit anti-SGEF anticorps

Antigène: SGEF (ARHGEF26) (rho Guanine Nucleotide Exchange Factor (GEF) 26 (ARHGEF26))

Épitope: AA 378-406

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SGEF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SGEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the Central region of human SGEF.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.48 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SGEF

Antigène: SGEF (ARHGEF26) (rho Guanine Nucleotide Exchange Factor (GEF) 26 (ARHGEF26))

Autre désignation: SGEF (ARHGEF26 Produits)

Synonymes: anticorps SGEF, anticorps AI303572, anticorps AW491953, anticorps 4631416L12Rik, anticorps 8430436L14Rik, anticorps RGD1562559, anticorps Sgef, anticorps CSGEF, anticorps HMFN1864, anticorps Rho guanine nucleotide exchange factor (GEF) 26, anticorps Rho guanine nucleotide exchange factor 26, anticorps Arhgef26, anticorps ARHGEF26

Sujet: SGEF activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.

Poids moléculaire: 97 kDa

ID gène: 26084

UniProt: Q96DR7