RGL4 anticorps (N-Term)

N° du produit ABIN5538799

Détail du produit anti-RGL4 anticorps

Antigène: RGL4 (Ral Guanine Nucleotide Dissociation Stimulator-Like 4 (RGL4))

Épitope: AA 98-125, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGL4 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RGL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-125 amino acids from the N-terminal region of human RGL4.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur RGL4

Antigène: RGL4 (Ral Guanine Nucleotide Dissociation Stimulator-Like 4 (RGL4))

Autre désignation: RGL4 (RGL4 Produits)

Synonymes: anticorps Rgr, anticorps ral guanine nucleotide dissociation stimulator like 4, anticorps RGL4

Sujet: Ral GDS (Ral guanine nucleotide dissociation stimulator) is a guanine nucleotide exchange factor (GEF) that activates Ral and is implicated in oncogenic Ras-induced cell transformation. RGL4 (ral guanine nucleotide dissociation stimulator-like 4), also known as Rgr, is a 473 amino acid protein that localizes to the cytoplasmic vesicle of cells. Belonging to the GEF family of proteins, RGL4 induces phosphorylation of ERKs, p38 and JNK kinases, and it increases the levels of GTP bound forms of Ral and Ras. Ras activation is crucial for the transforming activity of RGL4. Due to its similarity to Ral GDS, RGL4 may be implicated in carcinogenesis.

Poids moléculaire: 52 kDa

ID gène: 266747

UniProt: Q8IZJ4