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NUDT15 anticorps (C-Term)

NUDT15 Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5538826
  • Antigène Voir toutes NUDT15 Anticorps
    NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
    Épitope
    • 15
    • 8
    • 6
    • 1
    • 1
    AA 89-118, C-Term
    Reactivité
    • 24
    • 12
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 25
    Lapin
    Clonalité
    • 25
    Polyclonal
    Conjugué
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp NUDT15 est non-conjugé
    Application
    • 20
    • 16
    • 16
    • 14
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This NUDT15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-118 amino acids from the C-terminal region of human NUDT15.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product NUDT15 Anticorps primaire
  • Indications d'application
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100

    For FACS starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
    Autre désignation
    NUDT15 (NUDT15 Produits)
    Synonymes
    anticorps MTH2, anticorps RP11-90M2.1, anticorps 6530403O17, anticorps A730068G11Rik, anticorps nudix hydrolase 15, anticorps nudix (nucleoside diphosphate linked moiety X)-type motif 15, anticorps NUDT15, anticorps Nudt15
    Sujet
    Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear (By similarity). May have a role in DNA synthesis and cell cycle progression throught the interaction with PCNA.
    Poids moléculaire
    19 kDa
    ID gène
    55270
    UniProt
    Q9NV35
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