CKMT1 anticorps (N-Term)

N° du produit ABIN5539129

Détail du produit anti-CKMT1 anticorps

Antigène: CKMT1 (Creatine Kinase, Mitochondrial 1, Ubiquitous (CKMT1))

Épitope: AA 55-84, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CKMT1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This CKMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the N-terminal region of human CKMT1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CKMT1

Antigène: CKMT1 (Creatine Kinase, Mitochondrial 1, Ubiquitous (CKMT1))

Autre désignation: CKMT1 (CKMT1 Produits)

Synonymes: anticorps fb37h03, anticorps fb69a12, anticorps wu:fb37h03, anticorps wu:fb69a12, anticorps Mt-CK, anticorps ScCKmit, anticorps UbCKmit, anticorps mi-CK, anticorps Ckmt1, anticorps creatine kinase, mitochondrial 1, anticorps creatine kinase, mitochondrial 1, ubiquitous, anticorps ckmt1, anticorps Ckmt1

Sujet: Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase.

Poids moléculaire: 47 kDa

ID gène: 1159, 548596

UniProt: P12532