MLK4 anticorps (N-Term)

N° du produit ABIN5539282

Détail du produit anti-MLK4 anticorps

Antigène: MLK4 (KIAA1804) (Mitogen-Activated Protein Kinase Kinase Kinase MLK4 (KIAA1804))

Épitope: AA 33-62, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLK4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This MLK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human MLK4.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur MLK4

Antigène: MLK4 (KIAA1804) (Mitogen-Activated Protein Kinase Kinase Kinase MLK4 (KIAA1804))

Autre désignation: MLK4 (KIAA1804 Produits)

Synonymes: anticorps MLK4, anticorps RP5-862P8.2, anticorps dJ862P8.3, anticorps Mlk4, anticorps mKIAA1804, anticorps mitogen-activated protein kinase kinase kinase 21, anticorps MAP3K21, anticorps Map3k21

Sujet: Mixed-lineage kinases (MLKs) function as mitogen-activated protein kinase kinase kinases (MAP3Ks), activating the p38 and JNK signaling cascades. Systematic mutational analyses of tyrosine kinases reveal that a minimum of 30 % of colorectal cancer contain at least one mutation in the tyrosine kinases, sampling of colorect cancer cells suggest an important role of MLK4 in this process.

Poids moléculaire: 114 kDa

ID gène: 84451

UniProt: Q5TCX8