CLIC5 anticorps (Isoform 1)

N° du produit ABIN5540213

Détail du produit anti-CLIC5 anticorps

Antigène: CLIC5 (Chloride Intracellular Channel 5 (CLIC5))

Épitope: AA 160-173, Isoform 1

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CLIC5 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Specificité: This antibody recognizes CLIC5a, a 32 kDa protein which is component of actin complexes. Cross reactivity with CLIC5b was not determined.

Purification: Protein-A affinity chromatography (> 95% by SDS-PAGE)

Immunogène: KLH-conjugated peptide corresponding to the amino acids 160-173 of human CLIC5a

Clone: CLIC5-02

Isotype: IgG2b

Information d'application

Indications d'application: Flow cytometry. Western blot.

Protocole: 1. Wegner B, Al-Momany A, Kulak SC, Kozlowski K, Obeidat M, Jahroudi N, Paes J, Berryman M, Ballermann BJ: CLIC5A, a component of the ezrin-podocalyxin complex in glomeruli, is a determinant of podocyte integrity. Am J Physiol Renal Physiol. 2010 Jun298(6):F1492-503.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 95 % by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CLIC5

Antigène: CLIC5 (Chloride Intracellular Channel 5 (CLIC5))

Autre désignation: clic5 (CLIC5 Produits)

Synonymes: anticorps MST130, anticorps MSTP130, anticorps 5730531E12Rik, anticorps B330005L24, anticorps Gm322, anticorps jbg, anticorps clic5, anticorps im:6907594, anticorps zgc:77538, anticorps CLIC5, anticorps zgc:101827, anticorps chloride intracellular channel 5, anticorps chloride intracellular channel 5b, anticorps chloride intracellular channel 5a, anticorps chloride intracellular channel 5 L homeolog, anticorps CLIC5, anticorps Clic5, anticorps clic5b, anticorps clic5a, anticorps clic5.L

Sujet: CLIC5a belongs to the family of chloride intracellular channel (CLIC) proteins, all sharing a highly conserved C terminus and variable N terminus. Human CLIC5 is transcribed in two isoforms, 32 kDa CLIC5a (251 amino acids) and 49 kDa CLIC5b (410 amino acids). These proteins exist in a soluble form and their function as ion channels in vitro has not been fully confirmed in vivo. CLIC5a is a component of complexes of actin, ezrin, and several other actin-associated proteins and is important for functionality of actin-based structures.

UniProt: Q9NZA1

Pathways: Sensory Perception of Sound