NR1I2 anticorps (AA 1-142)

N° du produit ABIN5542364

Détail du produit anti-NR1I2 anticorps

Antigène: NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))

Épitope: AA 1-142

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NR1I2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purification: purified

Immunogène: Purified recombinant fragment of human NR1I2 (AA: 1-142) expressed in E. coli.

Clone: 1D12G1

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur NR1I2

Antigène: NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))

Autre désignation: NR1I2 (NR1I2 Produits)

Synonymes: anticorps BXR, anticorps ONR1, anticorps PAR, anticorps PAR1, anticorps PAR2, anticorps PARq, anticorps PRR, anticorps PXR, anticorps SAR, anticorps SXR, anticorps PXR.1, anticorps PXR.2, anticorps PXR1, anticorps mPXR, anticorps bxr, anticorps nr1i2, anticorps onr1, anticorps xonr1, anticorps nuclear receptor subfamily 1 group I member 2, anticorps nuclear receptor subfamily 1, group I, member 2, anticorps nuclear receptor subfamily 1 group I member 2 S homeolog, anticorps NR1I2, anticorps Nr1i2, anticorps nr1i2.S, anticorps nr1i2

Sujet:

Description: This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.,

Aliases: BXR, PAR, PRR, PXR, SAR, SXR, ONR1, PAR1, PAR2, PARq

Poids moléculaire: 49.8 kDa

ID gène: 8856

HGNC: 51529

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway