TCL1A anticorps (AA 10-104)

N° du produit ABIN5542543

Détail du produit anti-TCL1A anticorps

Antigène: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Épitope: AA 10-104

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TCL1A est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: purified

Immunogène: Purified recombinant fragment of human TCL1A (AA: 10-104) expressed in E. coli.

Clone: 2E3A5

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur TCL1A

Antigène: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Autre désignation: TCL1A (TCL1A Produits)

Synonymes: anticorps TCL1A, anticorps Tcl1a, anticorps TCL1, anticorps Tcl1, anticorps T-cell leukemia/lymphoma 1A, anticorps T cell lymphoma breakpoint 1, anticorps TCL1A, anticorps Tcl1, anticorps Tcl1a

Sujet:

Description: Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).

Aliases: TCL1

Poids moléculaire: 13.5 kDa

ID gène: 8115

HGNC: 8115

Pathways: Stem Cell Maintenance