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CD97 anticorps (Extracellular Domain, N-Term)

CD97 Reactivité: Souris WB, IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN401030
  • Antigène Voir toutes CD97 Anticorps
    CD97
    Épitope
    • 16
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-512, Extracellular Domain, N-Term
    Reactivité
    • 67
    • 10
    • 4
    • 1
    • 1
    Souris
    Hôte
    • 53
    • 20
    • 2
    • 2
    Lapin
    Clonalité
    • 57
    • 20
    Polyclonal
    Conjugué
    • 46
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD97 est non-conjugé
    Application
    • 45
    • 33
    • 29
    • 26
    • 13
    • 13
    • 10
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificité
    This antibody is directed against the CD97 protein. A BLAST analysis was used to suggest cross reactivity with CD97 proteins from Mouse (100 %) and Rat (74 %). Only 49 % homology is noted for the Human homologue. Reactivity against CD97 from other sources is not known.
    Réactivité croisée (Details)
    Species reactivity (expected):Rat.
    Species reactivity (tested):Mouse, Human, Chimpanzee.
    Purification
    Affinity chromatography on Protein A
    Immunogène
    Recombinant protein corresponding to amino acids 1-512 (extracellular domain) of mouse CD97 protein
    Isotype
    IgG
    Top Product
    Discover our top product CD97 Anticorps primaire
  • Indications d'application
    Immunofluorescence: 1/1000 - 1/5000. Western Blot: 1/1000 - 1/5000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with 0.1 mL deionized water (or equivalent).
    Concentration
    5.0 mg/mL (UV absorbance at 280 nm)
    Buffer
    0.02 M Potassium Phosphate, 0.12 M NaCl, pH 7.2, 0.01 % (w/v) Sodium Azide, None
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    CD97
    Autre désignation
    CD97 (CD97 Produits)
    Synonymes
    anticorps AA409984, anticorps TM7LN1, anticorps adhesion G protein-coupled receptor E5, anticorps Adgre5, anticorps ADGRE5
    Sujet
    CD97 is a membrane antigen that is either constitutively expressed or induced by activation on cells of the immune system including hematopoietic cells. Particularly high levels of expression are also seen in the lung and the thymus gland. In the spleen, expression is detected on most myeloid cells and variable portions of T cells, B cells and NK cells. In humans, CD97 expression is upregulated during lymphocyte activation on various epithelial cancer cells including colon, thyroid, stomach, and esophagus. One high affinity ligand that has been identified for CD97 is the integrin alpha 5 beta 1. CD97 engagement of endothelial alpha 5 beta 1 results in increased angiogenesis. Signals generated through CD97 are thought to result in Rho activation and the regulation of motility. Antibodies against CD97 are suitable for exploring various mouse genetic models of cancer, angiogenesis, and inflammation. CD97 can be proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit. Multiple isoforms have been identified for this protein.Synonyms: Leukocyte antigen CD97
    ID gène
    26364
    NCBI Accession
    NP_001156501
    UniProt
    Q9Z0M6
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