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c-MYC anticorps

MYC Reactivité: Humain, Souris, Poisson zèbre (Danio rerio) WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN357365
  • Antigène Voir toutes c-MYC (MYC) Anticorps
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    Reactivité
    • 375
    • 169
    • 123
    • 15
    • 14
    • 13
    • 13
    • 13
    • 9
    • 9
    • 8
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Poisson zèbre (Danio rerio)
    Hôte
    • 296
    • 99
    • 7
    • 3
    • 2
    • 1
    Lapin
    Clonalité
    • 287
    • 120
    Polyclonal
    Conjugué
    • 197
    • 32
    • 27
    • 26
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp c-MYC est non-conjugé
    Application
    • 307
    • 142
    • 96
    • 83
    • 80
    • 65
    • 58
    • 28
    • 26
    • 17
    • 15
    • 14
    • 12
    • 11
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects MYC.
    Purification
    Protein A column, followed by peptide affinity purification
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding T58 of human MYC.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MYC Anticorps primaire
  • Indications d'application
    ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    Autre désignation
    C-Myc (MYC Produits)
    Synonymes
    anticorps MRTL, anticorps MYCC, anticorps bHLHe39, anticorps c-Myc, anticorps CMYC, anticorps c-myc, anticorps C-MYC, anticorps LOC100136746, anticorps ARC, anticorps B430311C09Rik, anticorps MYC, anticorps NOP, anticorps Nop30, anticorps RNCMYC, anticorps mMyc, anticorps AU016757, anticorps Myc2, anticorps Niard, anticorps Nird, anticorps cmyc, anticorps zc-myc, anticorps c-myc II, anticorps myc-B, anticorps myc2, anticorps myc1, anticorps CMyc, anticorps zgc:55680, anticorps CG10798, anticorps D-Myc, anticorps DM, anticorps DMYc, anticorps Dm, anticorps Dmel\CG10798, anticorps Dmyc, anticorps EG:BACN5I9.1, anticorps anon-WO03040301.171, anticorps bHLHe57, anticorps c-MYC, anticorps d-myc, anticorps dMYC, anticorps dMyc, anticorps dMyc1, anticorps da, anticorps dm, anticorps dm/dMyc, anticorps dm/myc, anticorps dmyc, anticorps dmyc1, anticorps l(1)G0139, anticorps l(1)G0354, anticorps l(1)G0359, anticorps myc, anticorps MYC proto-oncogene, bHLH transcription factor, anticorps v-myc myelocytomatosis viral oncogene homolog, anticorps nucleolar protein 3 (apoptosis repressor with CARD domain), anticorps myelocytomatosis oncogene, anticorps MYC proto-oncogene, bHLH transcription factor a, anticorps MYC proto-oncogene, bHLH transcription factor L homeolog, anticorps MYC proto-oncogene, bHLH transcription factor S homeolog, anticorps v-myc myelocytomatosis viral oncogene homolog (avian), anticorps MYC proto-oncogene, bHLH transcription factor b, anticorps CG10798 gene product from transcript CG10798-RB, anticorps MYC, anticorps LOC100136746, anticorps Nol3, anticorps Myc, anticorps myca, anticorps myc.L, anticorps myc.S, anticorps mycb
    Sujet
    MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of the gene encoding MYC have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.Synonyms: BHLHE39, Class E basic helix-loop-helix protein 39, Myc proto-oncogene protein, Transcription factor p64
    Poids moléculaire
    48804 Da
    ID gène
    4609, 9606
    UniProt
    P01106
    Pathways
    Signalisation p53, Cycle Cellulaire, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, L'effet Warburg
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