ROR2 anticorps (N-Term)

N° du produit ABIN359930

Détail du produit anti-ROR2 anticorps

Antigène: ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ROR2 est non-conjugé

Application: Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to ROR2.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ROR2.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Références pour anticorps anti-ROR2 (ABIN359930)

Arabzadeh, Hossein, Salehi-Dulabi, Zarnani: "WNT5A-ROR2 is induced by inflammatory mediators and is involved in the migration of human ovarian cancer cell line SKOV-3." dans: Cellular & molecular biology letters, Vol. 21, pp. 9, (2017) (PubMed).

Détails sur ROR2

Antigène: ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

Autre désignation: ROR2 (ROR2 Produits)

Synonymes: anticorps BDB, anticorps BDB1, anticorps NTRKR2, anticorps Ntrkr2, anticorps mRor2, anticorps ROR2, anticorps bdb, anticorps bdb1, anticorps Xror2, anticorps ntrkr2, anticorps MGC97773, anticorps LOC100219935, anticorps ror2, anticorps xror2, anticorps receptor tyrosine kinase like orphan receptor 2, anticorps receptor tyrosine kinase-like orphan receptor 2, anticorps receptor tyrosine kinase like orphan receptor 2 L homeolog, anticorps ROR2, anticorps Ror2, anticorps ror2, anticorps ror2.L

Sujet: ROR2 is a tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. This Type I membrane protein is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Defects in ROR2 are a cause of brachydactyly type B1 (BDB1). BDB1 is an autosomal dominant skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In BDB1 the middle phalanges are short but in addition the terminal phalanges are rudimentary or absent. Both fingers and toes are affected. The thumbs and big toes are usually deformed. Defects in ROR2 are a cause of recessive Robinow syndrome (RRS). RRS is an autosomal disorder characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly and a dysmorphic facial appearance. The protein contains 1 frizzled (FZ) domain, 1 immunoglobulin-like C2-type domain, and 1 kringle domain.Synonyms: NTRKR2, Tyrosine-protein kinase transmembrane receptor ROR2

ID gène: 4920, 9606

UniProt: Q01974

Pathways: Signalisation RTK, Signalisation WNT