DUSP1 anticorps (C-Term)

N° du produit ABIN374121

Détail du produit anti-DUSP1 anticorps

Antigène: DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Séquence: SYLQSPITTS PSC

Specificité: This antibody detects DUSP1 at C-term.

Réactivité croisée (Details): Species reactivity (expected):Canine (Dog), Bovine.
Species reactivity (tested):Human, Mouse, Rat.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Synthetic peptide from C-Terminus of Human DUSP1 (NP_004408.1) Genename: DUSP1

Information d'application

Indications d'application: Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 0.3-1 μg/mL. Approx.40 kDa band observed in Human lysates of HeLa(calculated MW of 39.0 kDa according to NP_004408.1). Immunohistochemistry: 3-5 μg/mL. In paraffin embedded Human Prostate shows strongcytoplasm staining of secretory cells in the glands.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DUSP1

Antigène: DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))

Autre désignation: DUSP1 / MKP1 (DUSP1 Produits)

Synonymes: anticorps CL100, anticorps HVH1, anticorps MKP-1, anticorps MKP1, anticorps PTPN10, anticorps 3CH134, anticorps Mkp1, anticorps Ptpn16, anticorps DUSP1, anticorps U19515, anticorps erp, anticorps mkp-1, anticorps cb269, anticorps sb:cb269, anticorps zgc:55920, anticorps id:ibd2586, anticorps wu:fd19g02, anticorps wu:fe50g09, anticorps XCL100, anticorps dual specificity phosphatase 1, anticorps dual specificity phosphatase 1 S homeolog, anticorps DUSP1, anticorps Dusp1, anticorps dusp1, anticorps dusp1.S

Sujet: The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.Synonyms: CL100, Dual specificity protein phosphatase 1, Dual specificity protein phosphatase hVH1, MAP kinase phosphatase 1, MKP-1, PTPN10, Protein-tyrosine phosphatase CL100, VH1

ID gène: 1843

NCBI Accession: NP_004408

UniProt: P28562