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FOXO3 anticorps (C-Term)

FOXO3 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Porc WB, EIA Hôte: Chèvre Polyclonal unconjugated
N° du produit ABIN374440
  • Antigène Voir toutes FOXO3 Anticorps
    FOXO3 (Forkhead Box O3 (FOXO3))
    Épitope
    • 30
    • 16
    • 13
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 176
    • 130
    • 121
    • 9
    • 8
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat, Chien, Boeuf (Vache), Porc
    Hôte
    • 172
    • 5
    • 1
    • 1
    Chèvre
    Clonalité
    • 162
    • 17
    Polyclonal
    Conjugué
    • 71
    • 15
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp FOXO3 est non-conjugé
    Application
    • 113
    • 61
    • 52
    • 35
    • 28
    • 27
    • 14
    • 14
    • 14
    • 14
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Séquence
    C-GAKQASSQSW VPG
    Specificité
    This antibody recognizes FKHRL1/FOXO3A.
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse, Rat, Canine, Porcine, Bovine.
    Species reactivity (tested):Human.
    Purification
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
    Immunogène
    Peptide from the C Terminus of the protein sequence according to according to NP_001446.1. Genename: FOXO3
    Top Product
    Discover our top product FOXO3 Anticorps primaire
  • Indications d'application
    Peptide ELISA: 1/32,000. Western Blot: Approx 90 kDa band observed in human Brain and Heart lysates (calculatedMW of 71.0 kDa according to NP_001446 and NP_963853). Recommended concentration: 0.1 - 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    FOXO3 (Forkhead Box O3 (FOXO3))
    Autre désignation
    FOXO3 / FKHRL1 (FOXO3 Produits)
    Synonymes
    anticorps AF6q21, anticorps FKHRL1, anticorps FKHRL1P2, anticorps FOXO2, anticorps FOXO3A, anticorps zgc:92176, anticorps wu:fb50g02, anticorps wu:fi33f07, anticorps Fkhrl1, anticorps Foxo3a, anticorps FoxO3A, anticorps 1110048B16Rik, anticorps 2010203A17Rik, anticorps C76856, anticorps Fkhr2, anticorps FOXO-3, anticorps FOXO3, anticorps foxo3a, anticorps xfoxo3, anticorps foxO3, anticorps foxO, anticorps fkhr, anticorps foxo5, anticorps wu:fj65a12, anticorps zFkhr, anticorps forkhead box O3, anticorps forkhead box O3A, anticorps forkhead box O3 L homeolog, anticorps forkhead box O3b, anticorps FOXO3, anticorps foxo3a, anticorps Foxo3, anticorps foxo3.L, anticorps foxo3, anticorps foxO3, anticorps foxo3b
    Sujet
    FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Forkhead transcription factors of the FoxO subfamily are emerging as a shared component among pathways regulating diverse cellular functions, such as differentiation, metabolism, proliferation, and survival. Their transcriptional output is controlled via a two tiered mechanism of phosphorylation and acetylation. FOXO3A is a transcriptional activator which triggers apoptosis in the absence of survival factors. It recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. FOXO3a has been shown to induce cell growth arrest to effect tumor suppression and FOXO3A genotype is strongly associated with human longevitySynonyms: AF6q21 protein, FOXO3A, Forkhead box protein O3, Forkhead in rhabdomyosarcoma-like 1
    ID gène
    2309
    NCBI Accession
    NP_001446
    UniProt
    O43524
    Pathways
    Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
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