SERPINI2 anticorps (Internal Region)

N° du produit ABIN374538

Détail du produit anti-SERPINI2 anticorps

Antigène: SERPINI2 (serpin Peptidase Inhibitor, Clade I (Pancpin), Member 2 (SERPINI2))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SERPINI2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody is expected to recognize both reported isoforms (NP_006208.1 and NP_001012303.1).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine and (Dog).
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence C-KGDWKQKFRKEDTQ, from the internal region of the protein sequence. Genename: SERPINI2

Information d'application

Indications d'application: Peptide ELISA: Antibody detection limit dilution: 1/64000. Western Blot: 0.3-1 μg/mL. Approx 40 kDa band observed in Human Pancreas lysates (calculated MW of 46.0 kDaaccording to NP_006208.1 and 47.0 kDa and NP_001012303.1). Immunohistochemistry on Paraffin Sections: 3 μg/mL. In paraffin embedded Human Pancreas, shows cytoplasmic staining of acinar cels and ofrare cells in the islets of Langerhans.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preserative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SERPINI2

Antigène: SERPINI2 (serpin Peptidase Inhibitor, Clade I (Pancpin), Member 2 (SERPINI2))

Autre désignation: SERPINI2 (SERPINI2 Produits)

Synonymes: anticorps Spi14, anticorps MEPI, anticorps PANCPIN, anticorps PI14, anticorps TSA2004, anticorps serpin family I member 2, anticorps serpin peptidase inhibitor, clade I (pancpin), member 2 L homeolog, anticorps serpin peptidase inhibitor, clade I (pancpin), member 2, anticorps serine (or cysteine) peptidase inhibitor, clade I, member 2, anticorps SERPINI2, anticorps serpini2.L, anticorps Serpini2

Sujet: MEP1 is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. It may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.Synonyms: MEPI, Myoepithelium-derived serine protease inhibitor, PI14, Pancpin, Protease inhibitor 14, TSA2004

ID gène: 5276

NCBI Accession: NP_006208

UniProt: O75830