UCP2 anticorps (Internal Region)

N° du produit ABIN374813

Détail du produit anti-UCP2 anticorps

Antigène: UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp UCP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Séquence: C-DSVKQFYTKG SEH

Specificité: This antibody recognizes Uncoupling protein 2 / UCP2. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse, Rat, Canine (Dog).

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide from from the internal region of Human UCP2 (NP_003346.2). Genename: UCP2

Information d'application

Indications d'application: Peptide ELISA: 1/4000. Western Blot: 0.2 - 1 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Tris buffered saline, pH~7.3 0.02% Sodium Azide 0.5% BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.

Date de péremption: 12 months

Références pour anticorps anti-UCP2 (ABIN374813)

Liu, Shim, Nguyen, Gibbons, Mitchell, Poirier: "Tempol protects cardiomyocytes from nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity." dans: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 139, Issue 1, pp. 133-41, (2014) (PubMed).

Détails sur UCP2

Antigène: UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))

Autre désignation: SLC25A8 / UCP2 (UCP2 Produits)

Synonymes: anticorps UCP2, anticorps DKFZp470P1633, anticorps ucp2, anticorps MGC53319, anticorps MGC75881, anticorps cb74, anticorps ATUCP2, anticorps K19M22.21, anticorps K19M22_21, anticorps uncoupling protein 2, anticorps BMIQ4, anticorps SLC25A8, anticorps UCPH, anticorps Slc25a8, anticorps mitochondrial uncoupling protein 2, anticorps uncoupling protein 2, anticorps uncoupling protein 2 (mitochondrial, proton carrier) L homeolog, anticorps uncoupling protein 2 (mitochondrial, proton carrier), anticorps uncoupling protein 1, anticorps PTRG_09289, anticorps UCP2, anticorps LOC100282746, anticorps ucp2.L, anticorps ucp2, anticorps ucp1, anticorps Ucp2

Sujet: UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. UCP2 gene is expressed in many tissues, with the greatest expression in skeletal muscle. UCP2 is thought to play a role in non shivering thermogenesis, obesity and diabetes.
Alternate names: Mitochondrial uncoupling protein 2, Solute carrier family 25 member 8, UCP 2, UCP-2, UCPH

ID gène: 7351, 9606

UniProt: P55851

Pathways: Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Proton Transport