SLC12A6 anticorps (Internal Region)

N° du produit ABIN374883

Détail du produit anti-SLC12A6 anticorps

Antigène: SLC12A6 (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6))

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC12A6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: SRHIDVCSKT KE

Specificité: This antibody detects Solute carrier family 12 member 6. It is expected to recognise all 6 reported isofoms (NP_598408.1, NP_005126.1, NP_001035959.1, NP_001035960.1, NP_001035961.1, NP_001035962.1)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide from the internal region of the Human SLC12A6 (NP_001035959.1, NP_001035960.1, NP_001035961.1, NP_001035962.1, NP_005126.1, NP_598408.1. Genename: SLC12A6

Information d'application

Indications d'application: Peptide ELISA: limit dilution 1: 16000. Western blot: 0.1-0.3 μg/mL. Approx 120 kDa band observed in Human Heart and Kidneylysates (calculated MW ranging 121-120 kDa according to NP_598408.1, NP_005126.1,NP_001035959.1, NP_001035960.1, NP_001035961.1, NP_001035962.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SLC12A6

Antigène: SLC12A6 (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6))

Autre désignation: SLC12A6 (SLC12A6 Produits)

Synonymes: anticorps Kcc3, anticorps ACCPN, anticorps KCC3, anticorps KCC3A, anticorps KCC3B, anticorps 9530023I19Rik, anticorps gaxp, anticorps solute carrier family 12, member 6, anticorps solute carrier family 12 member 6, anticorps Slc12a6, anticorps SLC12A6

Sujet: K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The SLC12A6 protein is activated by cell swelling induced by hypotonic conditions. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy (ACCPN). ACCPN is characterised by severe progressive sensorimotor neuropathy, mental retardation, dysmorphic features, and partial or complete agenesis of the corpus callosum. The SLC12Ag gene is a candidate gene for schizophrenia and has also been associated with bipolar disease.Synonyms: Electroneutral, K-Cl cotransporter 3, KCC3, Solute carrier family 12 member 6

ID gène: 9990

NCBI Accession: NP_001035959

UniProt: Q9UHW9