SLC47A1 anticorps (Internal Region)

N° du produit ABIN375104

Détail du produit anti-SLC47A1 anticorps

Antigène: SLC47A1 (Solute Carrier Family 47, Member 1 (SLC47A1))

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC47A1 est non-conjugé

Application: Western Blotting (WB)

Séquence: C-PEHPQDGAKL SRKQ

Specificité: This antibody is specific to SLC47A1/MATE-1 (Internal).

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography.

Immunogène: Peptide with sequence from the internal region (near C-Terminus) of the protein sequence according to NP_060712.2.

Information d'application

Indications d'application: Peptide ELISA: Antibody detection limit dilution 1/64,000. Western Blot: (0.1-0.3 μg/mL)A approx. 60 kDa band is observed in Human Kidney lysates. An additional band of unknownidentity was also consistently observed at 20 kDa. This band was successfully blocked byincubation with the immunizing peptide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SLC47A1

Antigène: SLC47A1 (Solute Carrier Family 47, Member 1 (SLC47A1))

Autre désignation: SLC47A1 (SLC47A1 Produits)

Synonymes: anticorps MATE1, anticorps 1300013J15Rik, anticorps AI036982, anticorps mMATE1, anticorps zgc:113362, anticorps SLC47A1, anticorps DKFZp469B1821, anticorps RGD1311123, anticorps solute carrier family 47 member 1, anticorps solute carrier family 47, member 1, anticorps solute carrier family 47 (multidrug and toxin extrusion), member 1, anticorps MATE1, anticorps multidrug and toxin extrusion protein 2-like, anticorps SLC47A1, anticorps Slc47a1, anticorps slc47a1, anticorps LOC100125995, anticorps LOC100220385

Sujet: Transporters are expressed in a wide variety of tissues where they perform the critical function of enabling anionic and cationic chemicals of exogenous and endogenous origin to cross otherwise impermeable cell membranes. The multidrug and toxin extrusion (MATE) transporters mediate cellular efflux of a variety of organic cations, including many drugs, and are involved in excretion of toxic electrolytes through urine and bile. Members of the MATE family share homology with the bacterial MATE protein family, which is responsible for drug resistance. MATE1 (multidrug and toxin extrusion protein 1), also known as SLC47A1, is a 570 amino acid multi-pass membrane protein that predominantly localizes to the plasma membrane but is also found in intracellular organelles. Expressed in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney, MATE1 is responsible for the secretion of cationic drugs across the brush border membranes. MATE1 exists as three isoforms, which are produced by alternative splicing events.Synonyms: MATE-1, MATE1, Multidrug and toxin extrusion protein 1, Solute carrier family 47 member 1

ID gène: 55244, 9606

UniProt: Q96FL8